byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledg...
byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a g...
byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine resea...
byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and predi...
byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated appr...
byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
This timely guide to kinase inhibitor drug development is the first to cover the entire drug pipeline, from target identification to compound development and cl...
byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The...
byRaimund Mannhold,Hugo Kubinyi,Gerd Folkers
Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human ...
byHugo Kubinyi,Stephen Hanessian,Gerd Folkers
The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in th...
byRaimund Mannhold,Gerd Folkers,Hugo Kubinyi,Johannes Kirchmair
The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.The authors provide more than a systemati...
byJörg Holenz,Raimund Mannhold,Hugo Kubinyi,Gerd Folkers
In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies i...
byAlexander Dömling,Raimund Mannhold,Hugo Kubinyi,Gerd Folkers
Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from...
byNathan Brown,Hugo Kubinyi,Raimund Mannhold,Gerd Folkers
Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism.As such, it provid...
byBruce Roth,Hugo Kubinyi,Karen Lackey,Gerd Folkers,Raimund Mannhold
Edited by two renowned medicinal chemists who have pioneered the development of personalized therapies in their respective fields, this authoritative analysis o...
byHugo Kubinyi,Michel Hamon,Raimund Mannhold,José Vela,Gerd Folkers,Rafael Maldonado
This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major dise...